itching caused by intrathecal injection of morphine in cesarean section
Conditions
Interventions
Control group:intravenously injects 4ml of normal saline twice
Butorphanol group:intravenously injects 4ml of 1mg butorphanol and 4ml of normal saline
Ondansetron group:intravenously injects 4ml of 8mg ondansetron and 4ml of normal saline were injected intravenously
Combination group:intravenously injects 4ml of 1mg butorphanol and 4ml of 8mg ondansetron
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective cesarean section at the General Hospital of the Northern Theater Command; 2. Voluntarily participate and sign the informed consent; 3. ASA II; 4. Term pregnancy; 5. Aged 20-40 years; 6. No contraindications for spinal anesthesia; 7. Perform subarachnoid block and block successfully (the plane reaches T6 and above); 8. Morphine 200ug was used for postoperative analgesia during subarachnoid block.
Exclusion criteria
Exclusion criteria: 1. Mental illness, unable to communicate normally, refusing to participate in the trial, or unable to give informed consent; 2. Severe cardio-cerebral and lung diseases, including unstable angina, myocardial infarction, ventricular dysfunction, and increased intracranial pressure; 3. Severe pregnancy-induced hypertension; 4. Gastrointestinal diseases, including gastrointestinal obstruction; 5. Liver insufficiency; 6. Motion sickness and obvious history of nausea and vomiting during pregnancy; 7. Preoperative skin allergy, acute and chronic pruritus; 8. Opioid analgesics and sedatives have been used recently; 9. Use antipruritic drugs before surgery; 10. Related drug allergies; 11. Subarachnoid block failure or poor anesthesia effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of itching; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesia score;Sedation score; | — |
Countries
China
Contacts
Public ContactCao Huijuan
General Hospital of Northern Theater Command
Outcome results
None listed