Study on pathogenesis of osteoarthritis

Mir-454-3p regulates PPAR?mediated oxidative stress-induced chondrocyteapoptosis in osteoarthritis and the intervention effect of Angelica Sinensis Polysaccharide

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050762

Enrollment

Unknown

Registered

2021-09-04

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

osteoarthritis group:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients admitted for total knee arthroplasty; 2. The admission diagnosis was knee osteoarthritis.

Exclusion criteria

Exclusion criteria: After admission examination, it was judged that the operation could not be tolerated.

Design outcomes

Primary

Measure	Time frame
Oxidative stress;	—

Countries

China

Contacts

Public ContactZhuang Chao

Department of Orthopedics, Changzhou Second Hospital Affiliated to Nanjing Medical University

zhuangchao911@163.com+86 13584328757

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026