Clinical application of NOX index monitoring in patients undergoing general anesthesia

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050756

Enrollment

Unknown

Registered

2021-09-04

Start date

2021-09-02

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depth of anesthesia monitoring in patients undergoing general anesthesia during surgery

Interventions

BIS Monitoring Team (Group B):BIS monitoring

BIS+NOX monitoring group (BN group):BIS monitoring and NOX monitoring

Eligibility

Sex/Gender

All

Age

12 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged >= 12 years, ASA grade I-III; 2.Patients undergoing endotracheal intubation under general anesthesia; 3.In line with ethics, patients voluntarily took the test and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are unable to communicate effectively with researchers; 2. Combined with severe heart, liver, kidney and other organic diseases; 3. Suspected of long-term use or abuse of narcotic sedative analgesics; 4. Patients with contraindications or allergies to related drugs and methods; 5. Emergency surgery.

Design outcomes

Primary

Measure	Time frame
blood pressure;heart rate;BIS index;NOX index;blood glucose;Serum glucocorticoid expression regulates kinase 1;Tumor necrosis factor-a;Interleukin-1ß;Interleukin-6;C reactive protein;cortisol;Alertness/Sedation Observation Score (OAA/S Score);Pain Number (NRS) Score;Postoperative pain APS-POQ-R score;Mini-Mental State Examination (MMSE) score;	—

Countries

China

Contacts

Public ContactXie Yubo

The First affiliated Hospital of Guangxi Medical University

1157817791@qq.com+86 18176883506

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026