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Efficacy and Safety of Modified Gegenqinlian Fomular for Advanced Colorectal Cancer (Damp Heat Accumulation Type): A Multicenter Randomized Controlled Trial

Efficacy and Safety of Modified Gegenqinlian Fomular for Advanced Colorectal Cancer (Damp Heat Accumulation Type): A Multicenter Randomized Controlled Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050754
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced colorectal cancer

Interventions

Sponsors

Shanxi Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged > 18 years, survival period >= 3 months; 2. Patients with colorectal cancer who meet the above-mentioned diagnostic criteria of Western medicine and TCM syndrome types, and have been diagnosed by definite pathology or cytology; 3. TNM stage is IV, patients with postoperative recurrence, metastasis or lost the opportunity for surgery without surgery, have not taken traditional Chinese medicine within the past 1 month; 4. No other primary tumors and serious heart, liver and kidney diseases; 5. Those who have follow-up telephone numbers and addresses, patients or their families who are willing to cooperate with follow-up visits, have relatively complete medical records, and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Non-primary colorectal cancer; 2. Those who are unable or unwilling to accept traditional Chinese medicine treatment; 3. The patient has developed intestinal obstruction and cannot take drugs, needs intravenous high-energy nutrition, or has malabsorption syndrome or other diseases that affect the absorption of the gastrointestinal tract, or has active peptic ulcer disease.

Design outcomes

Primary

MeasureTime frame
Quality of Life;TCM symptom score;progression-free survival;overall survival;

Secondary

MeasureTime frame
Karnofsky functional status score;size of tumor;tumor makers;tumor microenvironment;immune state;

Countries

China

Contacts

Public ContactLiu Likun

Shanxi Provincial Hospital of Traditional Chinese Medicine

llkun133@126.com+86 13623609166

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026