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Molecular biological analysis of the extraocular muscles in strabismus

Molecular biological analysis of the extraocular muscles in strabismus

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050746
Enrollment
Unknown
Registered
2021-09-03
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus

Interventions

oculomotor nerve paralytic strabismus group:none
abducent nerve paralytic strabismus group:None
nystagmus group:None
thyroid-associated ophthalmology group:None
Congenital extraocular muscle fibrosis group:None

Sponsors

Eye and Ear Nose and Throat Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Those who are in line with one of oculomotor paralytic strabismus, abducens paralytic strabismus, congenital extraocular muscle fibrosis, nystagmus, thyroid-related ophthalmopathy, and congenital strabismus, and extraocular muscle amputation is included in the surgical plan; 2. The subjects or their authorized persons have signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of other autoimmune or inflammatory diseases not related to strabismus in the eye or system; 2. History of ocular or systemic hormone or immunosuppressive use within 3 months; 3. History of orbital radiotherapy or drug injection; 4. Abnormal blood sugar and glycosylated hemoglobin indexes in patients with diabetes; 5. History of tumor.

Design outcomes

Primary

MeasureTime frame
Deviations;transcriptomics;Proteomics;Metabonomics;

Countries

Chian

Contacts

Public ContactWu Lianqun, Zhao Chen

Eye and Ear Nose and Throat Hospital Affiliated to Fudan University

wulianqun19@aliyun.com+86 21 64377134

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026