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Exploring the regulatory mechanism of kidney-tonifying and essence-filling therapy for aplastic anemia based on proteomics of blood exosomes

Exploring the regulatory mechanism of kidney-tonifying and essence-filling therapy for aplastic anemia based on proteomics of blood exosomes

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050734
Enrollment
Unknown
Registered
2021-09-03
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aplastic Anemia

Interventions

chronic aplastic anemia group:No
low-risk myelodysplastic syndrome group:No
normal volunteer group:No
Experimental group:Busui Shengxue Granules
Control Group:Reconstructed Blood-generating Tablet

Sponsors

The First Affiliated Hospital, Heilongjiang University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria for chronic aplastic anemia and low-risk myelodysplastic syndrome, and healthy volunteers; 2. Aged 18 to 80 years; 3. Agree to participate and sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding women, and women of childbearing age who plan to become pregnant within the past six months; 2. Patients with severe infection, bleeding and anemia recently; 3. Patients with serious heart, liver, kidney and other underlying diseases, or patients with other serious primary, secondary or mental diseases; 4. Those who are allergic to research drugs or ingredients; 5. Those who participated in other clinical experiments three months before enrollment; 6. Other situations that the investigator considers unsuitable to participate in clinical trials.

Design outcomes

Primary

MeasureTime frame
Clinical marker of blood exosome protein;Chinese medicine symptom score table;Blood cell analysis;

Secondary

MeasureTime frame
Biochemical tests;

Countries

China

Contacts

Public ContactWang Jinhuan

The First Affiliated Hospital, Heilongjiang University of Chinese Medicine

wjh_0304@163.com+86 13946127714

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026