Acute Ischemic Stroke
Conditions
Interventions
Experimental group:Adjustable Thrombectomy Device
Sponsors
Changzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 85 years; 2. 6= 6 or core infarct volume < 50 mL; (2) Posterior circulation: cerebellum and occipital lobe infarction: unilateral cerebellum and occipital lobe infarction core focus < 1/2 of the largest layer (the cerebellum and occipital lobe on the same side); (3) Brainstem infarction: the core infarct area does not exceed the midline; 5. Intracranial large vessel occlusion (intracranial carotid artery, middle cerebral artery M1/M2 segment, anterior cerebral artery A1/A2 segment, basilar artery, vertebral artery intracranial segment) confirmed by DSA segment, posterior cerebral artery); 6. The subjects or their legal representatives can understand the purpose of the trial, voluntarily participate and sign the written informed consent, and can be followed up.
Exclusion criteria
Exclusion criteria: 1. Life expectancy 3.0 or platelet count 22.2 mmol/L that cannot be controlled by drugs; 12. Hypertension that cannot be controlled by drugs (continuous systolic blood pressure > 185mmHg, or diastolic blood pressure > 110mmHg); 13. Epilepsy accompanied by stroke; 14. Other conditions judged by the investigator to be unsuitable for inclusion. Imaging exclusion criteria (CT/MR/DSA examination with the following evidence): 1. Intracranial hemorrhage (except for microhemorrhage, the investigator will determine whether to join the group after weighing the risk according to the location and number of microhemorrhages); 2. Intracranial mass effect or intracranial tumor (except meningioma); 3. Vascular occlusion in different blood supply areas (such as bilateral anterior circulation or anterior and posterior circulation); 4. The proximal vessels of the target vessels have occlusive lesions requiring treatment; 5. Common carotid artery occlusion, known or suspected target vessel is chronic occlusion; 6. Simultaneous occlusion of bilateral carotid systems; 7. Carotid artery dissection or arteritis may be possible; 8. The vascular path is tortuous, and the test/control device is difficult to reach the target position or difficult to recover.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of successful reperfusion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful reperfusion time;NIHSS score at 24 hours and 7 days after operation;Rate of mRS (0-2) subjects at 90 days after operation;Rate of rescue therapy; First pass successful reperfusion rate;Times of thrombectomy;Operating performance of the device; | — |
Countries
China
Contacts
Public ContactPeng Ya
Changzhou First People's Hospital
Outcome results
None listed