Correlation between biological characteristics of dental pulp stem cells with caries progression

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050726

Enrollment

Unknown

Registered

2021-09-03

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental caries

Interventions

control group:Nil

Enamel caries group:Nil

dentine caries(RDT>=2mm)group:Nil

dentine caries(0.5<=RDT<2mm)group:Nil

dentine caries(RDT<0.5mm)group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: The third molar with health, enamel caries (enamel color change, probe, X-ray and microCT imaging data), dentine caries (obvious caries, soft, sensitive to probing, transient sensitivity to cold stimulation, X-ray and microCT imaging data show residual dentine thickness RDT >= 2mm) dentine caries (obvious caries, soft, sensitive to probe, transient pain of cold stimulation, X-ray and microCT imaging data, 0.5<=RDT < 2mmand no puncture)dentine caries (obvious caries, soft, sensitive, transient pain of cold stimulation, X-ray and microCT imaging data, RDT < 0.5mm, and no puncture)were collected from young clinical volunteers aged 18-25 years. )There are 5 cases in each group.

Exclusion criteria

Exclusion criteria: The third molars with periodontal pulp disease, pulp degeneration and pulp necrosis.

Design outcomes

Primary

Measure	Time frame
Differentiation marker gene;Differentiation marker protein;	—

Countries

China

Contacts

Public ContactLiang Suxia

Tianjin Stomatological Hospital

lliangyuer@163.com+86 13516279423

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026