Clinical study on the relationship between serum amyloid A and apolipoprotein A-I and the severity and prognosis of sepsis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050713

Enrollment

Unknown

Registered

2021-09-03

Start date

2021-09-20

Completion date

Unknown

Last updated

2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

control group:No

sepsis group:No

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients (aged >=18 years); 2. Meet sepsis 3 criteria: presence of infection, combined SOFA score >= 2.

Exclusion criteria

Exclusion criteria: 1. Sepsis occurred in the past 1 month; 2. Long-term use of lipid-lowering drugs; 3. Hyperlipidemia; 4. Patients who have received antibiotic therapy within 72 hours before admission; 5. Pregnancy; 6. Organ transplantation; 7. Liver cirrhosis; 8. Patients with blood diseases; 9. Chronic organ dysfunction; 10. Administration of tumor or immunosuppressive agents; 11. Patients with terminal disease; 12. Eliminate patients who were sedated with propofol during the course of the disease; 13. Eliminate patients who received parenteral nutrition during the course of the disease.

Design outcomes

Primary

Measure	Time frame
Apolipoprotein A1;serum amyloid A;	—

Secondary

Measure	Time frame
high density lipoprotein;C reactive protein;procalcitonin;	—

Countries

China

Contacts

Public ContactYu Jiangquan

Northern Jiangsu People's Hospital

yujiangquan2021@163.com+86 18051060659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026