Lumbar disc herniation
Conditions
Interventions
Control group:None
experimental group: Dexmedetomidine
Sponsors
Guangzhou Panyu Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients who underwent posterior lumbar discectomy decompression + bone graft fusion and internal fixation; 2. Aged 18 to 60 years; 3. The ASA I or II.
Exclusion criteria
Exclusion criteria: 1. Those with a history of glaucoma, acute conjunctivitis, corneal disease, and iris disease; 2. Recently used drugs that have an impact on IOP; 3. Serious cardiovascular diseases such as severe hypertension, diabetes, arrhythmia, myocardial infarction; 4. For patients with liver and kidney insufficiency, if the hemodynamic fluctuation is too large, the sample will be excluded; 5. Unable to communicate before surgery and non-compliance with tests; 6. Those who are allergic to dexmedetomidine; 7. Patients with moderate to severe anemia: preoperative Hb < 90g/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;mean arterial pressure;intraocular pressure;central venous pressure;hemoglobin;Dosage of dexmedetomidine; | — |
Secondary
| Measure | Time frame |
|---|---|
| age;gender;The operation time;Bleeding volume; | — |
Countries
China
Contacts
Public ContactHe Zhongxian
Guangzhou Panyu Central Hospital
Outcome results
None listed