chronic obstructive pulmonary disease
Conditions
Interventions
AECOPD eosinophil reduction group:None
AECOPD eosinophils increased group:None
sCOPD eosinophils increased group:None
sCOPD eosinophils reduction group:None
Health control group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40 to 80 years; 2. GOLD grade 2 and above (FEV1/FVC<70% after bronchodilator inhalation, FEV1<80% predicted value); 3. AECOPD is moderate to severe attack; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with other chronic respiratory diseases such as tuberculosis, tumor, bronchiectasis, pulmonary fibrosis; 2. Patients with serious cardiovascular disease, liver and kidney, blood and other systemic primary diseases; 3. Patients with asthma, allergic rhinitis, eczema, eosinophilic pneumonia and other diseases that may lead to eosinophilia; 4. Those who cannot cooperate with the project plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of eosinophils;interleukin-22; | — |
Countries
China
Contacts
Public ContactJiang Hongli
West China Hospital, Sichuan University
Outcome results
None listed