Association of Insulin Resistance With Postoperative Delirium and CSF Biomarkers for Alzheimers Disease Among Elderly Fracture Patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050675

Enrollment

Unknown

Registered

2022-09-01

Start date

2022-01-10

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Delirium group:None

non-delirium group:None

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 65 years; 2. ASA classification: I-III; 3. Patients undergoing elective fracture repair surgery; 4. Voluntarily participated and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Previous history of neurological or clinically significant neurovascular disease; 2. Long-term use of psychotropic drugs, chronic analgesics and other medical history or history of alcohol abuse; 3. Severe cardiopulmonary insufficiency; 4. Severe liver and kidney insufficiency before surgery; 5. Refuse to perform spinal anesthesia; 6. Patients participating in other clinical trials.

Design outcomes

Primary

Measure	Time frame
postoperative delirium score;	—

Secondary

Measure	Time frame
Delirium severity;ß-amyloid;The incidence of postoperative cognitive impairment 7 days after surgery;	—

Countries

China

Contacts

Public ContactLiu Peng

The Third Hospital of Hebei Medical University

liupeng2010aa@126.com+86 13284473704

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026