Efficacy assessment of phentolamine and lidocaine subcutaneously under ultrasound guidance on radial artery catheterization in pediatric patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050672

Enrollment

Unknown

Registered

2021-09-01

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

radial artery catheterization in pediatric patients

Interventions

Control group1:0.5 ml saline subcutaneous injection

Control group2:5 µg/kg phentolamine in 0.5 ml solution subcutaneous injection

Experimental group:5 µg/kg phentolamine with 4mg/kg lidocaine in 0.5 ml solution subcutaneous injection

Eligibility

Sex/Gender

All

Age

No minimum to 2 Years

Inclusion criteria

Inclusion criteria: 1. Aged less than 2 years; 2. ASA is classified as I-III; 3. Use general anesthesia; 4. Radial artery puncture and catheterization are required for invasive blood pressure monitoring during the operation.

Exclusion criteria

Exclusion criteria: 1. Peripheral vascular disease affects upper extremity function; 2. Severe upper extremity arteriosclerosis; 3. Severe renal insufficiency; 4. Severe peptic ulcer; 5. Those who are allergic to phentolamine or lidocaine; 6. Those who underwent radial artery puncture recently; 7. Allen's test is positive; 8. Trauma, hematoma, infection, etc. in the radial artery puncture area; 9. Shock or severe arrhythmia.

Design outcomes

Primary

Measure	Time frame
Radial artery diameter;	—

Countries

China

Contacts

Public ContactKong Erliang

The 988th Hospital of Joint Logistic Support Force of PLA

kel1992@126.com+86 13917506501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026