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Effects of different end expiratory carbon dioxide partial pressures on intracranial pressure and postoperative cognition

Effects of different end expiratory carbon dioxide partial pressures on intracranial pressure and postoperative cognition

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050664
Enrollment
Unknown
Registered
2021-09-01
Start date
2021-09-10
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric carcinoma

Interventions

Experimental group1:End respiratory carbon dioxide 30±3mmHg
Experimental group2:End respiratory carbon dioxide 40±3mmHg
Experimental group3:End respiratory carbon dioxide 50±3mmHg

Sponsors

The First Affiliated Hospital of Wannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years; 2. ASA classification: I ~ III; 3. Female; elective laparoscopic gynecological surgery; 4. Use total intravenous anesthesia; 5. BMI: 1824 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Severe mental illness; 2. Combined with severe liver, kidney and other system diseases; 3. Patients who have used antiemetic drugs or experienced nausea and vomiting within 24 hours before surgery; 4. Patients with a history of ophthalmic surgery or neurosurgery; 5. Patients with a history of smoking and motion sickness.

Design outcomes

Primary

MeasureTime frame
Mini-mental State Examination score;—

Countries

China

Contacts

Public ContactGuo Wenjun

The First Affiliated Hospital of Wannan Medical College

gwj8581@sina.com+86 13605532244

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026