refractory chemotherapy induced thrombocytopenia
Conditions
Interventions
Sponsors
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Solid tumors diagnosed with refractory CIT, defined as failure of treatment with Eltrombopag and recombinant human thrombopoietin (rhTPO); 2. Platelets below 25x10^9/L at least 4 weeks before enrollment; 3. Aged 18 to 80 years.
Exclusion criteria
Exclusion criteria: 1. Severe comorbidities associated with cardio-cerebrovascular,liver and kidney or psychosis; 2. Associate with severe arrhythmia,such as rapid atrial fibrillation,atrial flutter,paroxysmal ventricular tachycardia and ect; 3. Women in pregnancy, preparation for pregnancy or breast feeding period; 4. Nearly three months have enrolled in other clinical trials or be enrolling in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficacy;cumulative number of days of platelet response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Early platelet count predicts efficacy;safety; | — |
Countries
China
Contacts
Public ContactWu Dijiong
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed