Breast lesions
Conditions
Interventions
Gold Standard:pathological diagnosis
examination 
in 
and 
contrast-enhanced 
ultrasound 
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patient is a female patient, aged 18 to 80 years, who is admitted to the breast department or other clinical department of the hospital. 2. The diagnosis of breast BI-RADS class 4 nodules by imaging examination in our hospital or a tertiary hospital of the same level; 3. The diameter of the nodule is less than 30mm (due to the limitation of the size of the SWE sampling frame); 4. Be informed about the study, sign an informed consent form, and voluntarily accept shear wave elastography and contrast-enhanced ultrasound examinations; 5. Those who are assessed as having a high malignant tendency agree and cooperate with needle biopsy, rotational biopsy or surgical treatment, and finally obtain a pathological diagnosis; 6. No acute coronary syndrome or clinically unstable ischemic heart disease symptoms have occurred recently.
Exclusion criteria
Exclusion criteria: 1. Incomplete clinical and pathological data; 2. After breast augmentation, during pregnancy or breastfeeding; 3. The target mass has undergone invasive operations such as radiotherapy and chemotherapy or puncture and resection; 4. There is a history of adverse reactions with the use of sulfur hexafluoride or phospholipids; 5. Have a history of asthma, urticaria, etc.; 6. History of malignant tumor and other cachexia patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| imaging index;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactZhang Bo
Xiangya Hospital of Central South University
Outcome results
None listed