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Establishing a precise system of damage early-warning and intervention for obstructive sleep apnea hypopnea syndrome: a multiple center prospective real-world study

Establishing a precise system of damage early-warning and intervention for obstructive sleep apnea hypopnea syndrome: a multiple center prospective real-world study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050548
Enrollment
Unknown
Registered
2021-08-28
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea hypopnea syndrome

Interventions

Case series:No

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate in this clinical study and sign the informed consent; 2. No gender restrictions, baseline age >= 18 years old; 3. Keep complete baseline demographic information, medical history information, anthropometric data, questionnaire information, PSG data, and biochemical index information; 4. The total duration of effective recording data for the baseline examination is >= 4 hours; 5. Willing to cooperate to complete the follow-up; 6. Not participating in other clinical research projects within the past 3 months.

Exclusion criteria

Exclusion criteria: 1. Previously diagnosed with other sleep-disordered breathing diseases other than OSAHS, such as central sleep apnea syndrome, sleep-related alveolar hypopnea disorder, sleep-related hypoxemia, etc.; 2. Suffering from congenital cardiovascular, respiratory, metabolic, neurological, digestive, urinary and other system diseases, such as congenital ventricular septal defect, thoracic deformity, type 1 diabetes, glycogenosis, Down syndrome, congenital digestive tract or Urinary tract malformations, etc.; 3. Suffering from severe mental system diseases such as mania and schizophrenia; 4. Suffering from tuberculosis, AIDS, syphilis and other infectious diseases; 5. Pregnant women; 6. Long-term use of steroid hormones or hormone replacement therapy; 7. Acute inflammatory response period; 8. Unable to cooperate in completing various inspections and tests, or unable to provide biological samples.

Design outcomes

Primary

MeasureTime frame
Height;Weight;Neck circumference;waist circumference;hip circumference;tongue position;tonsil position;blood pressure;liver function;Kidney function;blood glucose;Blood lipids;glycosylated hemoglobin;Fasting plasma insulin;Fasting blood glucose;Ventricular wall thickness;Left ventricular mass;Carotid inner diameter;Carotid intima thickness;Carotid plaque;Epworth Sleepiness Scale;Pittsburgh Sleep Quality Index;Quebec Sleep Questionnaire Score;Montreal Cognitive Assessment Test Form Score;Mini-Mental State Examination Score;Hospital Anxiety and Depression Scale Score;Functional sleep outcome questionnaire Score;Trail Making Test A Score;

Countries

China

Contacts

Public ContactYin Shankai

Shanghai Sixth People's Hospital

yinshankai@china.com+86 18930177096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026