Parkinson's disease
Conditions
Interventions
Experimental group:Reishi Mushroom Extract Treatment
Control group:None
Sponsors
Xuanwu Hospital of Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of "clinically probable PD" for MDS primary Parkinson's disease; 2. Aged 30 to 80 years at the time of diagnosis of Parkinson's; 3. H-Y clinical grade <= 2; 4. The UPDRS ? score is between 10-30 (including 10 and 30); 5. The course of the disease does not exceed 5 years; 6. Have not received anti-Parkinsonian drugs or other treatments, or have discontinued treatment drugs for more than 2 weeks (drugs include dopamine preparations, dopa receptor agonists, COMT inhibitors, MAO inhibitors, antan, amantadine); 7. Agree to participate in this experiment, sign the informed consent form, and be willing to abide by the relevant experimental regulations, take medication on time and come to review regularly; 8. Agree to receive only experimental drug treatment in the next 1.5 years, and receive anti-Parkinsonian drug treatment as prescribed by a doctor when necessary.
Exclusion criteria
Exclusion criteria: 1. Have a history of mental symptoms or mental illness; 2. Cognitive dysfunction (MDSE score 24 points); 3. Participated in other drug experiments within the past 3 months; 4. Severe liver and kidney dysfunction (more than 3 times the normal average); 5. Are using anti-Parkinsonian drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parkinson's Assessment Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Constipation scale;Cognitive Function Scale;Senile Dementia Rating Scale;Schwab-England Disability Scale;Depression Scale;Parkinson's Syndrome Scale of Chinese medicine;Parkinson's Pain assessment Scale;Olfactory Argentine Questionnaire;Parkinson's sleep scale; | — |
Countries
China
Contacts
Public ContactLi Jun
The First Affiliated Hospital of Anhui University of Chinese Medicine
Outcome results
None listed