Analysis of peripheral blood immune cell subsets in patients with sepsis based on single-cell transcriptome sequencing technology and study on the mechanism of sepsis immune dysfunction

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050534

Enrollment

Unknown

Registered

2021-08-28

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Case series:None

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 75 years, regardless of gender; 2.Patients with sepsis are selected according to the diagnostic criteria in the "2016 International Guidelines for the Diagnosis and Treatment of Severe Sepsis and Septic Shock"; 3.The subject voluntarily participates in the study and signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. Have an immunosuppressive state, including a history of malignant tumors, long-term use of hormones or immunosuppressive drugs, HIV or other immunodeficiency diseases, and a history of organ transplantation; 3. Expected stay in ICU is less than 24 hours; 4. Be diagnosed with sepsis in a foreign hospital or other department before transferring to ICU.

Design outcomes

Primary

Measure	Time frame
Single Cell RNA Seq Synovium;clinical data;	—

Countries

china

Contacts

Public ContactRen Di

Shenzhen Second People's Hospital

59192570@qq.com???

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026