Effect of Remimazolam on Postoperative Delirium in Elderly Patients undergoing Hip Surgery: A Prospective, Randomized, Controlled Study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050511

Enrollment

Unknown

Registered

2021-08-28

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Experimental group:remimazolam

control group:Midazolam

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. American society of anesthesiologist (ASA) classification II-III; 2. Aged >= 65 years; 3. No drugs that affect delirium were used before surgery; 4. Preoperative Minimum Mental State Examination (MMSE) scores were all greater than 24 points.

Exclusion criteria

Exclusion criteria: 1. Serious impairment of liver and kidney function; 2. Severe respiratory system or cardiovascular and cerebrovascular diseases; 3. Long-term use of sedatives or preoperative mental and nervous system diseases; 4. Patients with abnormal coagulation function or contraindications to spinal anesthesia such as anticoagulant drugs before surgery; 5. The patient refuses.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium;	—

Secondary

Measure	Time frame
Serum levels of IL-6;postoperative sedation and pain;Postoperative complications;	—

Countries

China

Contacts

Public ContactWang Xiaoyu

Beijing Tsinghua Changgung Hospital

wangxiaoyu1021@163.com+86 18600499139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026