A series of studies on the application of sodium bicarbonate Ringer's solution in target-directed fluid therapy for liver transplantation

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050486

Enrollment

Unknown

Registered

2021-08-28

Start date

2021-09-15

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:Perioperative use of sodium bicarbonate Ringer's solution

Control group:Perioperative infusion of Ringer's acetate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. End-stage liver disease caused by various reasons; 2. Primary liver cancer (liver cancer) without distant metastasis or invasion of large blood vessels; 3. Cardiopulmonary function can tolerate liver transplantation.

Exclusion criteria

Exclusion criteria: 1. Preoperative hypermagnesemia; 2. Hypothyroidism; 3. Patients who have been transplanted in combination with other organs; 4. The patient refuses to participate in clinical trials.

Design outcomes

Primary

Measure	Time frame
5% sodium bicarbonate usage;	—

Secondary

Measure	Time frame
Basic vital signs;Anastomotic effluent sodium, potassium and calcium concentrations;Intraoperative rescue use of various rescue drugs;Rehabilitation;	—

Countries

China

Contacts

Public ContactQie Xiaojuan

The Third Hospital of Hebei Medical University

qiexiaojuan@163.com+86 13103019189

Outcome results