Skip to content

Clinical study of liquid biopsy in membranous nephropathy based on urine exosomal proteome detection

Clinical study of liquid biopsy in membranous nephropathy based on urine exosomal proteome detection

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050481
Enrollment
Unknown
Registered
2021-08-27
Start date
2021-09-01
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

membranous nephropathy

Interventions

Gold Standard:kidney biopsy
Index test:types and amounts of proteins expressed in exosomes

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Plan a kidney biopsy to confirm the pathological type of kidney disease; 2. Sign the informed consent; 3. Aged over 18 years; 4. Have not undergone any invasive testing or treatment intervention.

Exclusion criteria

Exclusion criteria: 1. Combined with infectious diseases such as hepatitis B, hepatitis C, HIV; 2. Combined with cardiovascular and cerebrovascular diseases, tumors and other diseases; 3. Patients with severe infectious diseases; 4. Pregnant and lactating patients; 5. Patients with severely impaired immune response (such as hypogammaglobulinemia, severe CD4 or CD8 cell count reduction); 6. Other conditions deemed inappropriate by other clinicians to participate in this study.

Design outcomes

Primary

MeasureTime frame
exosomal protein CD26;;;;AUC of ROC;

Countries

China

Contacts

Public ContactCai Yanling

Shenzhen Second People's Hospital

caiyanling@secretech.com+86 13530802052

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026