None listed
Conditions
Interventions
Intervention Group:Ropivacaine combined with Dexmedetomidine within spinal and epidural space
Saline Control Group:Ropivacaine in combination with equivalent of saline
Sufentanil Control Group:Ropivacaine combined with Sufentanil within spinal and epidural space
Sponsors
Linquan County People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-40 years; 2. ASA I or II level; 3. Singleton pregnancy.
Exclusion criteria
Exclusion criteria: 1. Those who have gestational hypertension who need treatment; 2. Patients with liver, kidney or other end-organ diseases; 3. Placenta previa, placental abruption; 4. Preoperative heart rate less than 50 bpm/min with abnormal cardiac conduction or rhythm; 5. Allergic reactions to a2 adrenergic agonists or local anesthetics; 6. Patients with contraindications to spinal anesthesia; 7. Morbidly obese (body mass index > 38kg/m^2) and very short or very tall ( 180cm); 8. Refuse to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Movement pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to first rescue analgesic request;Number and dose of press within 48 hours after surgery;Postoperative rest and movement scores;Postoperative opioid-related side effects;Exhaust time;Time to get out of bed;Onset time of local block;Sensory block time;Degree of intraoperative traction reaction; | — |
Countries
China
Contacts
Public ContactCheng Xinqi
Outcome results
None listed