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Development of a Drum Tower Severity Scoring (DTSS) System for Pyrrolizidine Alkaloid-induced Hepatic Sinusoidal Obstruction Syndrome

Development of a Drum Tower Severity Scoring (DTSS) System for Pyrrolizidine Alkaloid-induced Hepatic Sinusoidal Obstruction Syndrome: a single-center retrospective diagnostic trial

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050417
Enrollment
Unknown
Registered
2021-08-27
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pyrrole alkaloid-related hepatic sinusoidal obstruction syndrome (PA-HSOS)

Interventions

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Sponsors

The Affiliated Drum Tower Hospital of Nanjing University Medical School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed according to the PA-HSOS Nanjing standard; 2. Receive anticoagulation combined with supportive treatment; 3. Aged 18-85 years.

Exclusion criteria

Exclusion criteria: 1. There are more than 2 other liver damage factors, such as excessive drinking, hepatotropic virus infection, autoimmune liver disease, etc.; 2. Multiple organ dysfunction (MODS) existed before anticoagulation therapy; 3. Malignant tumor; 4. Missing data; 5. The anti-coagulation bureau is unknown.

Design outcomes

Primary

MeasureTime frame
Specificity;Sensitivity;

Countries

China

Contacts

Public ContactZhuge Yuzheng

The Affiliated Drum Tower Hospital of Nanjing University Medical School

yuzheng9111963@aliyun.com+86 13770755008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026