Atelectasis
Conditions
Interventions
High positive end expiratory pressure (PEEP) group:PEEP = 10 cm H2O
Low positive end expiratory pressure (PEEP) group:PEEP = 5 cm H2O
Sponsors
Huashan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years; 2. BMI >=30 kg/m^2; 3. American Society of Anesthesiologists (ASA) class I-III; 4. Laparoscopic sleeve gastrectomy with no contraindications to surgery; 5. Patients and their families have signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with unresolvable air leak during mask compressions, tracheal intubation time > 5 min; 2. Patients with symptoms of upper respiratory tract infection or lung infection in the last 4 weeks, pulmonary CT indicating atelectasis or pneumonia; 3. Diseases affecting the thorax and pulmonary compliance such as corpus cavernosum, funnel chest, chronic obstructive pulmonary emphysema and acute respiratory distress syndrome; 4. History of neuromuscular dysfunction; 5. Presence of allergy or contraindication to conventional anesthetic drugs; 6. Expected difficult airway requiring awake intubation; 7. History of severe bronchial asthma; 8. History of severe cardiac disease with cardiac function class III-IV; 9. Patient is participating in other studies at the same time; 10. Pregnancy or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation;Atelectasis; | — |
Countries
China
Contacts
Public ContactWang Yingwei
Huashan Hospital of Fudan University
Outcome results
None listed