Ovulatory Infertility
Conditions
Interventions
Simple group:High-intensity focused ultrasound
Integrated group:High-intensity focused ultrasound (ovarian and uterine fibroids)
Sponsors
Shanghai Xuhui Central Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with ovulatory dysfunction aged >= 25 years, priority included in the diagnosis of premature ovarian insufficiency, refractory polycystic ovary syndrome (unilateral or bilateral ovarian diameter 2-9 mm follicles >= 20-30); 2. Not pregnant after receiving specialized treatment in reproductive center for more than 1 year; 3. Routine ovulation induction therapy, two cycles of treatment for anovulatory or oocyte retrieval 40 IU/L,FSH/LH > 2-3, antral follicle count(AFC) < 3-6 serum, anti-mullerian hormone(AMH) < 1 ng/ml; 6. Patients with irregular uterine bleeding and hyperandrogenemia and/or clinical manifestations of polycystic ovarian changes; 7. Patients with adenomyosis complicated with uterine fibroids.
Exclusion criteria
Exclusion criteria: 1. Infertility caused by fallopian tube,reproductive tract malformation,immune factors and other reasons; 2. Patients with hypothalamus and/or hypophysis, such as hypogonadotropin sex hypogonadism; 3. Complicated with cardiovascular,cerebrovascular,liver,kidney and hematopoietic system and other major diseases and abnormal secretion function of adrenal and thyroid glands; 4. Patients with hyperprolactinemia; 5. Patients with a history of abdominal surgery; 6. Patients with a history of pelvic inflammatory disease; 7. Patients with poor treatment compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate;Ovulation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex hormone;Ovarian reserve; | — |
Countries
China
Contacts
Public ContactXu Yonghua
Shanghai Xuhui Central Hospital
Outcome results
None listed