Onychomycosis
Conditions
Interventions
Experimental group:Terbinafine dissolvable microneedle
Control Group:Itraconazole
Sponsors
Shanghai Skin Disease Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. According to the history, physical signs and laboratory examination, the patients with onychomycosis were diagnosed clinically; 2. Direct microscopic examination and/or fungal culture were positive; 3. Aged >=18 years, male or female; 4. Patients with panychomycosis or proximal subungual onychomycosis (no apparent thickening of the nail plate), and OSI score 8-10.
Exclusion criteria
Exclusion criteria: 1. Local exudation or combined with active bacteria and virus infection; 2. Those suffering from neuropsychiatric diseases or being treated with other drugs that affect the curative effect; 3. Psoriasis patients; 4. Patients who had been treated with antifungal agents or glucocorticoids within 4 weeks before enrollment; 5. Patients who had topical antifungal drugs within 2 weeks before enrollment; 6. Participants in other drug trials within 30 days before screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onychomycosis Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mycological detection; | — |
Countries
China
Contacts
Public ContactTan Jingwen
Shanghai Skin Disease Hospital
Outcome results
None listed