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Retrospective study on the prognostic effect and safety of sodium bicarbonate Ringer’s solution in critically ill patients

Retrospective study on the prognostic effect and safety of sodium bicarbonate Ringer’s solution in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050350
Enrollment
Unknown
Registered
2021-08-26
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU inpatients

Interventions

Sodium bicarbonate Ringer's solution group:None
Normal saline group:None

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Length of ICU stay>=24h; 2.Use more than 500ml of sodium bicarbonate Ringer's solution or more than 500ml of normal saline.

Exclusion criteria

Exclusion criteria: 1.Age<14 years; 2.Pregnant or lactating woman; 3.Patients with hypermagnesemia or hypothyroidism; 4.The necessary clinical data information is incomplete; 5.One patient uses sodium bicarbonate Ringer's solution or normal saline and sodium lactate Ringer's solution, sodium acetate Ringer's solution or other colloidal solution.

Design outcomes

Primary

MeasureTime frame
30-day mortality rate;Whether or not to receive kidney replacement therapy;Creatinine was more than twice the baseline;—

Secondary

MeasureTime frame
Length of intensive care unit stay;Time of using ventilator;Time of using vasoactive drugs;—

Countries

China

Contacts

Public ContactLi Shusheng

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

lishusheng@hust.edu.cn+86 13971086498

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026