Acquired Immune Deficiency Syndrome, AIDS
Conditions
Interventions
Sponsors
Chengdu Public Health Clinical Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Group A: HIV confirmed positive; Age >=18 years old; Did not receive any ART in the past. 2.Group B: HIV confirmed positive; Age >=18 years old; Use of ART program containing TDF for at least 1 year. 3.Group C: HIV confirmed positive; Age >=18 years old; Use of ART regimen without TDF for at least 1 year. 4.Group D: Age >=18 years old.
Exclusion criteria
Exclusion criteria: 1.Patients with hepatitis B and C; 2.Patients with hyperthyroidism (hyperparathyroidism), chronic kidney disease, diabetes, rheumatic diseases, hypogonadism, hypothalamic pituitary diseases and malignant tumors; 3.Long-term hormone users; 4.Women who use medroxyprogesterone for a long time; 5.Patients who drink a lot of alcohol for a long time; 6.Patients with severe liver and kidney dysfunction and heart failure; 7.Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of osteopenia/osteoporosis in groups A, B, C and D;Differences in the incidence of osteopenia/osteoporosis between group B and group C; | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence factors of bone mineral density in acquired immune deficiency syndrome patients;Effect of anti-retroviral therapy on bone mineral density in acquired immune deficiency syndrome patients; | — |
Countries
China
Contacts
Public ContactYang Tongtong
Chengdu Public Health Clinical Medical Center
Outcome results
None listed