Prediction of Efficacy of Acupuncture Treatment for Migraine Based on Machine Learning Algorithms: A DTI Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050333

Enrollment

Unknown

Registered

2021-08-26

Start date

2021-08-26

Completion date

Unknown

Last updated

2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Experimental group:Acupuncture treatment

Healthy control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients with migraine without aura were diagnosed according to the International Classification of Headache Disorders III (ICHD-3 beta); 2.Aged 18 to 65 years, right handedness; 3.A history of migraine for at least 1 year; 4.The frequency of migraine attack more than twice a month; 5.No acupuncture treatment or medication was used within 24 hours after the acute onset of migraine, and no preventive treatment for migraine during the past 3 months; 6.Sign written informed consent.

Exclusion criteria

Exclusion criteria: 1.Other types of primary headaches such as chronic migraine, tension-type headaches, nerve headache and cluster headache; 2.Any other secondary headaches or neurological diseases-headaches caused by intracranial diseases such as otolaryngological diseases, depression and Parkinson's disease; 3.Relatively severe life-threatening diseases, such as cardiovascular diseases, acute infectious diseases, hematological diseases, endocrine diseases, allergies or hemoptysis; 4.Use of prophylactic migraine medication and acupuncture treatment during the past three months. 5.Pregnancy, lactation and preparation for pregnancy; 6.Smoking, alcohol and drug abuse; 7.Patients with pain within 3 days before MRI scan; 8.Any contraindications of acupuncture treatment, such as hematological diseases and local infections, etc.; 9.Any contraindications for magnetic resonance imaging (MRI) exam, such as metal implants in the body, claustrophobia, etc.

Design outcomes

Primary

Measure	Time frame
Halving rate of headache days;	—

Secondary

Measure	Time frame
Visual analogue pain scale;Headache impact test;Migraine disability assessment questionnaire;Beck depression inventory;Manifest anxiety scale;	—

Countries

China

Contacts

Public ContactZhang Ya'nan

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

zhangyanan@bjzhongyi.com+86 15901119002

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026