lung protection
Conditions
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Aged>=18 years; 2.American Society of Anesthesiologists (ASA) classification I-III; 3.ARISCAT score >=26; 4.The postoperative length of stay is expected to exceed 24h; 5.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Pregnancy or breastfeeding; 2.Severe functional liver and kidney disease; 3.Pulmonary disease including COPD, pulmonary infection,bronchiectasis and asthma; 4.Subjects has contraindication for butorphanol; 5.Abuse of opioids; 6.Mental illness and communication disorder before surgery; 7.Patients on ventilators before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung function and respiratory mechanical parameters;Quality of recovery;Intraoperative hemodynamic indexes and intraoperative cumulative opioid use;Unplanned admission to intensive care unit;The incidence of postoperative adverse reactions;Number of effective compressions of analgesic pump and cumulative use of sufentanil;Concentration of CC16, IL-6, IL-10, ICAM-1, ET-1; | — |
Countries
China
Contacts
Public ContactLiu Su
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed