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Comparison of efficacy of remimazolam and propofol on induction and maintenance of anesthesia in elderly patients undergoing ureteroscopic laser lithotripsy

Comparison of efficacy of remimazolam and propofol on induction and maintenance of anesthesia in elderly patients undergoing ureteroscopic laser lithotripsy: a randomized, controlled, single-blind prospective study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050300
Enrollment
Unknown
Registered
2021-08-26
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urolithiasis

Interventions

Experimental group:Remazolam is a combination of intravenous anesthesia
Control group:Propofol was anesthetized by intravenous combination

Sponsors

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged>= 65 years old; 2.ASA grade I~II; 3.Laser lithotripsy under ureteroscope is proposed; 4.18.5kg/m^2 <= BMI <=23.9kg/m^2; 5.Sign informed consent.

Exclusion criteria

Exclusion criteria: 1.Allergic to benzodiazepines or esters; 2.History of long-term use of benzodiazepines; 3.History of alcoholism; 4.History of myasthenia gravis; 5.Mental disorders that are known to have diseases of the central nervous system or meet the diagnostic criteria of DSM; 6.Emergency operation.

Design outcomes

Primary

MeasureTime frame
Vital sign fluctuation;Dose and frequency of vasoactive drugs;Surgical interruption;

Secondary

MeasureTime frame
Induction time;Injection pain;Intraoperative use of opioid analgesics;Awakening time;Extubation time;Time of operation;Surgeon satisfaction;Postoperative nausea, vomiting, headache and other adverse reactions;Postoperation pain;

Countries

China

Contacts

Public ContactShangguan Wangning

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University

sgwning@163.com+86 13587637891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026