Bronchoscopy diagnosis and treatment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients plan to undergo painless bronchoscopy; 2.Aged >= 18 years; 3.ASA I~III; 4.Have completed relevant ancillary tests, such as routine blood, pulmonary function, liver and kidney function, and blood clotting function, etc.; 5.Patients have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Heart failure NYHA class 3 to 4, pulmonary heart disease CCS class 3 to 4; 2.OSAHS, COPD GOLD grade III-IV, pulmonary fibrosis, evidence of pulmonary alveoli, emphysema, pneumothorax, uncontrolled asthma; 3.End-stage liver disease, end-stage renal disease (GFR <15 ml/min); 4.Decreased basal oxygen saturation (resting SpO2 < 90%), SpO2 < 95% via NC oxygen (4L/min); 5.Basal sinus bradycardia (HR <60 beats/min) with significant bradycardia-related symptoms; 6.Pregnant, lactating women; 7.History of allergy to narcotic drugs, history of drug abuse; 8.History of coagulation disorders, tendency to rhinorrhea, habitual epistaxis, or nasal surgery; 9.A definite infection of the mouth, nose and throat; 10.Pacemakers or implantable cardioverter-defibrillators; 11.Emergency surgery; 12.Patients who are participating in other clinical trials; 13.Otherwise considered by the investigator to be unfit to participate in a clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global end-expiratory pulmonary impedance change;Region of interest; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia (SpO2<90%);Intervention measures and frequency of hypoxemia; | — |
Countries
China
Contacts
Shanghai Pulmonary Hospital, Tongji University