The Effect of Penehyclidine Hydrochloride Prevents Postoperative Nausea and Vomiting after Thyroid Surgery

Observation on the Effect of Prophylaxis of Nausea and Vomiting after Thyroidectomy with Long Thorning

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050278

Enrollment

Unknown

Registered

2021-08-25

Start date

2021-08-25

Completion date

Unknown

Last updated

2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

after thyroid surgery, postoperative nausea and vomiting

Interventions

Experimental group:Lumina + penehyclidine hydrochloride

Control group:Lumina + atropine

Eligibility

Sex/Gender

All

Age

24 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1.ASA I-II; 2.Aged 24 to 64 years; 3.Scheduled for total thyroidectomy with central compartment node dissection.

Exclusion criteria

Exclusion criteria: 1.Body mass index more than 30 kg/m^2; 2.Smoking; 3.History of PONV or motion sickness; 4.Severe cardiopulmonary disease; 5.Experienced hepatic or renal disease; 6.Medication with steroids, or cognitive impairment.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomiting and other adverse events;Operation completion condition;Vital signs after entry and induction of anesthesia;Adverse events and corresponding treatment;Adverse events during anaesthetic resuscitation;Diagnosis and surgical methods;Total anesthesia time;Total operation time;Extubation time;	—

Countries

China

Contacts

Public ContactLu Ting

Jiangsu Province Hospital

luting1489@163.com+86 13584082156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026