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Clinical study of dual-channel antithrombotic therapy for the prevention of left ventricular thrombosis in acute anterior wall myocardial infarction

Clinical study of dual-channel antithrombotic therapy for the prevention of left ventricular thrombosis in acute anterior wall myocardial infarction

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050255
Enrollment
Unknown
Registered
2021-08-24
Start date
2021-08-10
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

Experimental group:Ticagrelor and rivaroxaban
Control group:Traditional dual antiplatelet therapy

Sponsors

China-japan Union Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients conforming to acute anterior wall myocardial infarction after emergency PCI without left ventricular thrombosis confirmed by baseline color ultrasound.

Exclusion criteria

Exclusion criteria: 1.Active bleeding within 12 months, such as intracranial hemorrhage, hemorrhage of digestive tract and urogenital system; 2.Peptic ulcer within 6 months; 3.Liver and kidney diseases, chronic severe renal failure; Creatinine clearance was less than 20; 4.Atrial fibrillation or other thrombotic diseases, oral rivaroxaban; 5.Malignant tumor (expected survival of less than 1 year) and pregnancy status; 6.Confirmed or suspected blood system related diseases (except mild or moderate anemia); 7.Platelet deficiency (platelets <50x10^9/L); 8.CRUSADE score was greater than 50 points; 9.Younger than 18, older than 75; 10.Allergic to drugs used in this study; 11.Do not agree to participate in the researcher.

Design outcomes

Primary

MeasureTime frame
Rate of left ventricular thrombosis;

Secondary

MeasureTime frame
Adverse event;

Countries

China

Contacts

Public ContactZhang Wenqi

China-japan Union Hospital of Jilin University

13644407485@163.com+86 13644407485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026