Intravenous labor analgesia
Conditions
Interventions
Control group:Intravenous labor analgesia was not given
Fixed dose group:A fixed dose of remifentanil was given
Individualized dose group:Remifentanil dose varies according to labor process and individualized dose
Sponsors
Chongqing health center for women and children
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Contraindications of intraminal block in puerpera complicated with coagulation function abnormality, platelet abnormality, spinal malformation, puncture site infection, central nervous system disease and so on; 2. The puerpera refused to perform intraspinal labor analgesia due to fear; 3. Failure of intraspinal block or previous lumbar surgery or ineffective intraspinal analgesia; 4. Agree to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. History of opioid allergy, drug dependence, or drug addiction; 2. Complicated obstetric complications, such as pregnancy hypertension placenta previa scar uterus severe hypovolemia and so on; 3. Concomitant respiratory cardiovascular nervous system disease; 4. Abnormal renal and liver function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation score (Ramsay score), VAS pain grade;Fetal heart rate monitoring, Apgar score, Umbilical cord blood gas analysis;Remifentanil concentrations in umbilical cord venous blood and umbilical cord arterial blood;Concentrations of serum cortisol and plasma adrenergic corticotropin in puerpera; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators; | — |
Countries
China
Contacts
Public ContactCai Meng
Chongqing health center for women and children
Outcome results
None listed