Skip to content

The effect of surgical margin on prognosis of Siewert II / III gastric esophageal junction adenocarcinoma

A real world study on the effect of surgical margins on the prognosis of Siewert II / III gastroesophageal junction adenocarcinoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050226
Enrollment
Unknown
Registered
2021-08-22
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

experimental group:total gastrectomy

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients voluntarily joined the study and signed informed consent; 2. Aged from 18 to 75 years; 3. According to Seiwert's classification, they were type II and type III; 4. Patients whose clinical stage of radical resection was T2-4N0-2M0 (according to AJCC 8th edition stage) determined by CT and laparoscopy; 5. No anti-tumor treatment was received; 6. ECOG-PS score 0-1.

Exclusion criteria

Exclusion criteria: 1. Previous or concurrent malignant tumor; 2. Peritoneal metastasis or peritoneal cytology positive or retroperitoneal lymph node metastasis and other distant metastases (according to AJCC 8th Edition stage) could not be operated; 3. Non resectable factors were found, including unresectable tumor or contraindication of surgery; 4. Serious mental disorder; 5. Patients who have undergone emergency gastrectomy due to gastric cancer related complications (e.g., perforation, bleeding and obstruction); 6. According to the researcher's judgment, the patient has other factors that may affect the results of the study or cause the study to be terminated, alcoholism, drug abuse, other serious diseases (including mental illness) need to be treated together, there are serious laboratory abnormalities, accompanied by family or social factors, which will affect the safety of patients.

Design outcomes

Primary

MeasureTime frame
disease-free survival;

Secondary

MeasureTime frame
overall survival;optimum cutting edge distance;

Countries

China

Contacts

Public ContactPang Tao

Shanghai Changhai Hospital

pangtao7667@163.com+86 13764621777

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026