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A randomized controlled trial on the effect of different COS protocols in IVF

Study on the effect of a new trigger method on COS outcome

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050198
Enrollment
Unknown
Registered
2021-08-22
Start date
2021-08-23
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

experimental group 1:new trigger protocol
experimental group 2:HCG trigger
experimental group 3:HCG+Gnah
experimental group 4:Gnah
experimental group 5:a novel protocol

Sponsors

Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 20 to 38 years; 2. Basal FSH 5; 3. AMH>1.1ng/ml; 4. Body mass index: 18-28 Kg/M2.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to assisted reproductive technology or pregnancy contraindications; 2. Judging by the clinical experience of patients with uterine abnormalities affecting pregnancy, such as uterine malformations (single angle uterus, double angle uterus, double uterus, mediastinal uterus), adenomyosis, uterine fibroids (fibroids greater than 3 cm or within Membrane closely), submucosal uterine fibroids, intrauterine adhesions, endometrial polyps untreated, scar uterine, cervical conization patients; 3. History of recurrent miscarriage; 4. Endometriosis III-IV; 5. Chromosome abnormalities on either side of the couple; 6. People with alcoholism, addiction, or drug abuse habits.

Design outcomes

Primary

MeasureTime frame
Rate of fresh embryo transfer;

Secondary

MeasureTime frame
incidence of moderate/severe OHSS;Rate of fresh embryo transfer;Clinical pregnancy rate during transplantation period;fertilization rate;M2 rate;good embryo rate;implantation rate;miscarriage rate;cumulative live birth rate;hormone blood value;

Countries

china

Contacts

Public ContactChao Shibin

Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine

chaoshibin@163.com+86 18079111478

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026