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Assessing depression severity based on the detection of lymphocytes and its subcellular organelles: A prospective, single-center real-world clinical study

Assessing depression severity based on the detection of lymphocytes and its subcellular organelles: A prospective, single-center real-world clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050195
Enrollment
Unknown
Registered
2021-08-22
Start date
2021-08-31
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

case group:Nil

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis meets the international standards for depressive episodes in DSM-V; 2. The total score of 24 items of the Hamilton Depression Scale (HAMD) is greater than 20; 3. Patients with depression diagnosed by structured conversations by professional psychiatrists; 4. No history of epilepsy or glaucoma; 5. No immunomodulatory drugs have been taken in the past 6 months, and the woman has not been breastfeeding or pregnant; 6. Sign the informed consent form and participate voluntarily.

Exclusion criteria

Exclusion criteria: 1. Those with severe physical disease, liver and kidney function, blood routine examination and other obvious abnormalities; 2. Have taken immunosuppressive agents or immune enhancers within six months; 3. Have taken psychotropic drugs or antipyretic analgesics within half a month; 4. Those who have acute infection, fever, trauma, or inflammation within half a month; 5. Those who have received electrical aspiration therapy or sleep deprivation therapy within half a month; 6. Other organic mental disorders, and mental disorders caused by psychoactive substances and non-addictive substances, except for tobacco dependence.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;Sleep Belief Scale;Pittsburgh Sleep Scale;Epworth Sleepiness Scale;Stop Bang;

Secondary

MeasureTime frame
Hamilton Anxiey Scale;MoCA;

Countries

China

Contacts

Public ContactLou Zhongze

Ningbo First Hospital

lorenzo_87@163.com+86 15088864393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026