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Mechanism of Eosinophils Induced Remodeling of Esophageal Smooth Muscle in the Development and Prognosis of Achalasia

Mechanism of Eosinophils Induced Remodeling of Esophageal Smooth Muscle in the Development and Prognosis of Achalasia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100050193
Enrollment
Unknown
Registered
2021-08-22
Start date
2018-08-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achalasia

Interventions

achalasia group:Take esophageal muscle pathology
control group:Take esophageal muscle pathology

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diagnosed with achalasia clearly, no other systemic diseases and severe organic disease. With serious clinical symptoms, patients are treated voluntarily and understand the content of informed consent

Exclusion criteria

Exclusion criteria: Patients with previous gastric and/or esophageal surgery, Barrett’s esoph-ageal lesions, esophageal stricture, liver cirrhosis and/or esophageal var-ices, active esophagitis, connective tissue diseases, allergic diseases, pregnancy, hemopathy, hiatal hernia, and other coagulopathy

Design outcomes

Primary

MeasureTime frame
TGF-beta;alpha-SMA;collagen I;collagen III;—

Countries

China

Contacts

Public ContactWei Zhao

Tianjin Medical University General Hospital

weizhaohotstone@163.com+86 15022327482

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026