Construction and mechanism of prediction model of stroke rehabilitation effect based on motor imagination-brain computer interface

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050178

Enrollment

Unknown

Registered

2021-08-21

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

MI - BCI response group:The subjects underwent the first stage of mi-BCI-assisted upper limb function training, followed by the second stage of mi-BCI-assisted upper limb function training alone. At t

MI-BCI - non-response group - intervention group:The first stage of mi-BCI assisted upper limb functional training. Further individualized rehabilitation intervention was conducted according to the ma

MI-BCI - nonresponsive group - control group:Patients received BCI assisted upper limb function training

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of stroke formulated by the fourth National Conference on Cerebrovascular Diseases; 2. Ischemic stroke confirmed by brain CT or MRI, disease course >=6 months; 3. Stroke causes unilateral hand dysfunction, and Brunnstrom stage 1-3; 4. mini-Mental Status Examination 21-30 points, be able to complete the experiment; 5. Aged from 50 to 75 years; 6. Sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Previous history of upper limb fracture, deformity of upper limb, etc; 2. The condition is unstable or the condition changes occur during the experiment, which affects the experimental results; 3. Unable to complete the experiment due to serious heart, lung, liver and kidney and other important organ diseases; 4. Severe cognitive dysfunction or aphasia; 5. History of other neurological and psychiatric diseases and epilepsy; 6. Taking medications that reduce the threshold of seizures; 7. Any implanted device or metal may be affected by the magnetic field generated by TMS.

Design outcomes

Primary

Measure	Time frame
Action Research Arm Test;Fugl-Meyer assessment of upper extremity ;functional near-infrared spectroscopy;motor evoked potential;	—

Secondary

Measure	Time frame
Assessment of motor imagination function;Attention assessment;Assessment of emotional function;	—

Countries

China

Contacts

Public ContactLin Qiang

The Fifth Affiliated Hospital of Guangzhou Medical University

qianglin0925@gzhmu.edu.cn+86 18922497674

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026