Infertility
Conditions
Interventions
Fresh embryo transfer group:fresh embyo transfer
Frozen embryo transfer group:freeze all embryo and perform a frozen embryo transfer
Sponsors
Reproductive Medical Center, Shandong University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Women who undergo their first cycle of IVF, ICSI, or donor-sperm IVF; 2. Gn initiation dose >=150IU/d for ovulation induction patients with conventional regimen, including long regimen, short regimen and antagonist regimen; 3. Women who meet 2016 POSEIDON definition for poor prognosis, with number of oocytes retrieved <9 or with AFC<5 and/or AMH<1.2ng/ml.
Exclusion criteria
Exclusion criteria: 1. Women who used luteal phase protocol or progestin-primed protocol for ovarian stimulation which doesn't allow a fresh embryo transfer; 2. Women who are diagnosed with polycystic ovary syndrome based on Chinese criteria; 3. Women with hydrosalpinx diagnosed with HSG or ultrasonography; 4. Women with uterine malformation (unicornuate uterus or septate uterus) or a history of intrauterine adhesion; 5. Women with the number of previous spontaneous pregnancy loss>=3; 6. Women with contraindications for assisted reproduction technology or for pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;rate of multiple pregnancy;rate of pregnancy loss;rate of ectopic pregnancy;risk of maternal complications;risk of neonatal complications;birth weight;cumulative live birth rate; | — |
Countries
China
Contacts
Public ContactChen Zijiang, Wei Daimin
Reproductive Medical Center, Shandong University
Outcome results
None listed