heart failure
Conditions
Interventions
control group:common treatment
Sponsors
Xiamen Cardiovascular Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years old; 2. Acute decompensated heart failure was defined according to the patient profiling in heart failure for tailoring medical therapy, combined with symptoms, signs and laboratory results, and meet all the following conditions; (1) At least one symptom was worsened from baseline: 1) Dyspnea (dyspnea after exercising, paroxysmal nocturnal dyspnea or orthopnea); 2) Venous congestion of systemic circulation (edema of lower extremities, liver congestion, ascites); 3) Tissue hypoperfusion (oliguria or anuria, cold clammy limbs, consciousness disorder, hyperlacticacidemia or metabolic acidosis); (2) At least one of the following signs of heart failure: 1) Pulmonary edema on exam or by chest X ray; 2) Increased b-type natriuretic peptide or N-terminal prohormone BNP; 3) Abnormal cardiac structure and/or function by cardiac ultrasound; 3. The symptoms and signs are consistent with acute decompensated heart failure judged by the investigator; 4. Patients who have New York Heart Association Cardiac Function class III or IV symptoms at admission; 5. Clinical stability has been achieved for 24 hours after optimizing treatment; 6. Patient was independent with basic activities of daily living including the ability to ambulate independently (with or without the use of an assistive device) prior to admission.
Exclusion criteria
Exclusion criteria: 1. Acute coronary syndrome within 2 days, onset of chest pain within 8 hours; or combined with mechanical complications; 2. Fatal arrhythmia, high-grade atrioventricular block, new onset atrial fibrillation or atrial flutter; 3. Severe aortic valve stenosis; 4. Acute myocarditis, acute pericarditis, or acute infective endocarditis; 5. Severe hypertrophic obstructive cardiomyopathy; 6. Patients with chronic kidney disease stage 4 and 5 undergoing long-term hemodialysis or requiring long-term hemodialysis within the next 6 months; 7. A recent embolism, atrium or ventricular thrombosis, thrombophlebitis; 8. Patients who require a pacemaker, implantable cardioverter defibrillator (ICD), or ventricular assist device, or those awaiting cardiac transplantation within the next 6 months; 9. Those who had received standardized cardiac rehabilitation within the past 6 months; 10. Severe cognitive impairment (MMSE<=9 points); 11. Inability or unwillingness to comply with the study requirements; 12. Patients who dropped out or discharged during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| short physical performance battery; | — |
Secondary
| Measure | Time frame |
|---|---|
| cardiac function;psychological assessment;the quality of life; | — |
Countries
China
Contacts
Public ContactWu Linjing
Xiamen Cardiovascular Hospital of Xiamen University
Outcome results
None listed