Multicenter clinical study of poly cinnamol injection in the treatment of esophageal varices based on LDRF classification

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050147

Enrollment

Unknown

Registered

2021-08-18

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal varices

Interventions

Group 1:Continuous sclerotherapy with poly cinnamol injection

Group 2:ligation

Eligibility

Sex/Gender

All

Age

3 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 3 to 75 years old; 2. Liver cirrhosis caused by various causes; 3. Esophageal varices, according to LDRF classification, the indications for endoscopic treatment of esophageal varices are Le D1-3, Rf0-2, requiring elective or emergency treatment; 4. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Advanced liver cancer with portal vein tumor thrombus; 2. Hepatic encephalopathy, coma and other patients who cannot accept or cooperate with endoscopic treatment; 3. There is a possibility of ectopic embolism caused by huge gastrorenal, splenorenal shunt; 4. Serious cardiovascular diseases, including acute myocardial infarction, severe conduction block and heart failure; 5. Severe renal insufficiency; 6. Patients with other end-stage diseases; 7. Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
safety and effectiveness;	—

Contacts

Public ContactLinghu En-Qiang

PLA General Hospital

576489419@qq.com+86 13501233558

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026