Study on the mechanism of intra-articular injection in the treatment of knee osteoarthritis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100050133

Enrollment

Unknown

Registered

2021-08-17

Start date

2021-05-17

Completion date

Unknown

Last updated

2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee arthritis

Interventions

case series:intra-articular injection

Eligibility

Sex/Gender

All

Age

40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. No age limit, no gender limit; 2. Patients with intra-articular injection for knee osteoarthritis; 3. A sufficient amount (>1ml) of synovial fluid can be extracted during the first intra-articular injection; 4. It is expected to be able to complete 5 intra-articular injections in our hospital (the conventional course of treatment includes 5 times of fluid extraction and intra-articular injection); 5. The research subjects signed the ''Informed Consent''.

Exclusion criteria

Exclusion criteria: 1. The patient does not agree to donate biological samples or clinical information; 2. Combined with intra-articular infection.

Design outcomes

Primary

Measure	Time frame
Pain score;Cytokines;Flow cytometry typing;	—

Countries

China

Contacts

Public ContactJin Lixia

Zhongshan Hospital Affiliated to Fudan University

jinlixia0903@outlook.com+86 13817453035

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026