epilepsy
Conditions
Interventions
case series:None
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=14 years. 2. Newly diagnosed as epilepsy according to the 2017 International Anti-Epilepsy Federation (ILAE) standards. 3. Primary school education level above sixth grade, and MMSE>24. 4. Patients who have never previously used ASMs/ withdrawal medication > for 3 months. 5. Obtain the informed consent of the patient.
Exclusion criteria
Exclusion criteria: 1. Patients who failed to receive at least one efficacy/safety assessment after administration of antiepileptic drugs (ASMs). 2. Patients who are unable to cooperate or have difficulty recording seizures. 3. Poor medication compliance, that is, those who fail to take medication on time and frequently miss medication due to various reasons, those who do not follow the doctor's advice to increase or decrease the dose of medication, and those who add traditional Chinese medicine and home remedies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mini-mental state examination,MMSE;subjective cognitive function scale,ABNAS;objective neuropsychological rating scale;epilepsy quality of life rating scale,QOLIE-31;neurological disorders depression inventory for epilepsy,NDDI-E;generalized anxiety disorder,GAD-7;Pittsburgh sleep quality index,PSQI;responder rate of anti-epileptic treatment;incidence of adverse events;seizure-free rate;radiomics data;electroencephalogram (EEG);blood electrolytes;thyroid function;blood biochemistry;medication symptom distress scale;blood fat;routine urine test;cytokine 6 items (IL 2, 4, 6, 10, TNF-a, IFN);blood concentration; | — |
Countries
China
Contacts
Public ContactXu Huiqin
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed