Hematologic malignacy
Conditions
Interventions
case series:None
Sponsors
The First Affiliated Hospital of Medical College of Zhejiang University
Eligibility
Sex/Gender
All
Age
15 Years to 67 Years
Inclusion criteria
Inclusion criteria: 1. The subjects or their legal representatives signed the informed consent before the start of the clinical study. 2. Gender is not limited. Females of childbearing age have a negative pregnancy test within 14 days before starting the test drug. 3. Aged 15-67 years. 4. Subjects with malignant hematological diseases who received allogeneic peripheral blood stem cell transplantation for major ABO blood group incompatibility. 5. ECOG physical fitness score 0-2 points. 6. No major organ dysfunction.
Exclusion criteria
Exclusion criteria: 1. Combined with active infection; 2. Patients diagnosed with aplastic anemia before transplantation or patients who died within 2 months after transplantation; 3. Combined with secondary tumor; 4. Severe central nervous system disease or mental illness makes it impossible to choose to enter or withdraw from clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| cumulative incidence of blood cell transfusion independence;cumulative incidence of platelet transfusion independence;blood cell transfusion requirements;platelet transfusion requirements;cumulative incidence of graft versus host disease; | — |
Countries
China
Contacts
Public ContactHuang He
The First Affiliated Hospital of Medical College of Zhejiang University
Outcome results
None listed