coronary artery disease
Conditions
Interventions
Sponsors
The Affiliated Hospital of Shandong University of TCM
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for chronic stable angina pectoris. 2. CCS angina pectoris grades I to III. 3. Aged 30 to 70 years. 4. Those who are intolerant to nitrates. 5. The subjects voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute myocardial infarction, unstable angina pectoris, stable angina pectoris with exertion IV and other heart diseases; 2. Combined with poorly controlled hypertension and diabetes, severe cardiopulmonary insufficiency, severe arrhythmia (rapid atrial fibrillation, atrial flutter, paroxysmal ventricular tachycardia, etc.), use of pacemaker and history of cerebrovascular disease within 1 year ; 3. History or evidence of any of the following diseases during the screening period: severe cardiovascular and cerebrovascular diseases; active, recurrent digestive system ulcers or other diseases with bleeding risk; other serious diseases of the digestive system; combined with malignant tumors, hematological diseases or other serious or progressive diseases; combined with other mental diseases and unable to cooperate or unwilling to cooperate; 4. Any one of the laboratory test indicators before screening meets the following criteria: admission liver and kidney function prompts: ALT, AST > 1.5 times the upper limit of normal value, Cr > 1.2 times the upper limit of normal value (Refer to the normal range of laboratory tests in the research center); other clinically significant laboratory tests are abnormal, and the investigators judge that they are not suitable for inclusion; 5. Suspect or have a history of alcohol or drug abuse; 6. Pregnant, lactating patients or those who are planning to become pregnant in the near future and who are unwilling to use contraceptive measures; 7. Patients who have participated in clinical trials of other drugs within 3 months before enrollment; 8. The researchers believe that patients should not participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electrocardiogram;Changes of main symptoms of TCM;Blood stasis syndrome score;Seattle angina questionnaire;Patient-reported clinical outcome scale for coronary heart disease and angina pectoris; | — |
Countries
China
Contacts
Public ContactLi Yunlun
The Affiliated Hospital of Shandong University of TCM
Outcome results
None listed