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Evaluation the ovarian hyperstimulation outcomes in poor ovarian response women between GnRH antagonist and PPOS protocols: a prospective, randomized clinical trial

Evaluation the ovarian hyperstimulation outcomes in poor ovarian response women between GnRH antagonist and PPOS protocols: a prospective, randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100050036
Enrollment
Unknown
Registered
2021-08-16
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

GnRH antagonist group:GnRH antagonist protocol

Sponsors

Wuhan University Renmin Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. For patients diagnosed with POR according to the Bologna consensus, POR can be diagnosed if 2 of the following 3 criteria are met: (1) Advanced age (>= 40 years old) or other risk factors for poor ovarian response; (2) The number of oocytes retrieved by the conventional ovulation stimulation program in the past is = 1 year, with IVF or ICSI indications.

Exclusion criteria

Exclusion criteria: 1. Combined with other systemic serious diseases such as liver and kidney insufficiency systemic lupus erythematosus; 2. Patients diagnosed with premature ovarian failure; 3. Have used hormonal birth control within 3 months before enrollment; 4. Reproductive system malformations; 5. Patients who are planning to undergo preimplantation genetic testing (PGT); 6. Endometriosis patients.

Design outcomes

Primary

MeasureTime frame
Number of available embryos;

Secondary

MeasureTime frame
Number of oocyte retrieved;Fertilization rate;Rate of good quality embryo;Clinical pregnancy rate;Cycle cancellation rate;Time to pregnancy;

Countries

China

Contacts

Public ContactQi Qianrong

Wuhan University Renmin Hospital

qi_qianrong@126.com+86 17720480509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026