Stroke
Conditions
Interventions
tDCS Group: transcranial direct current stimulation
Median nerve stimulation group:median nerve electrical stimulation
control group:None
Sponsors
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for stroke patients: 1. Patient aged 18-75 years old; 2. After cerebral infarction or cerebral hemorrhage, 1 month<=onset time<=6 months; 3. The diagnosis conforms to the diagnostic points of various cerebrovascular diseases adopted by the Fourth National Cerebrovascular Disease Academic Conference in 1995; 4. Patients who have suffered a stroke for the first time or have had no sequelae in the past; 5. Stroke confirmed by head CT or MRI examination and excluded other obvious neurological diseases (such as encephalitis, hydrocephalus, etc.); 6. Have limb dysfunction; 7. Sinus rhythm; 8. The patient himself or his legal representative signed the informed consent. Inclusion criteria for healthy subjects: 1. Aged 18 to 75 male or female; 2. In good health, the chief complaint is no special discomfort, no special past history, and no abnormal laboratory imaging examination results; 3. No drinking, smoking, etc.; 4. Voluntary participation, the patient himself understands and signs the informed consent, and can complete the experiment according to the experimental protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with various severe arrhythmias; 2. Patients with serious primary diseases such as heart, liver, kidney and hematopoietic system; 3. Patients with autonomic dysfunction caused by other non-cerebrovascular causes (such as peripheral neuropathy, diabetic autonomic neuropathy, etc.); 4. Those who have a history of mental disorders and drug abusers in the past; 5. Stroke patients with major organ failure or critical illness; 6. Patients with malignant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epinephrine, norepinephrine, cortisol, aldosterone, renin, corticotropin, angiotensin II, IgF-1 levels;Heart rate variability (HRV) assessment;Upper Limb Movement Research Scale (ARAT); | — |
Countries
China
Contacts
Public ContactWu Yi
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University
Outcome results
None listed